OVARIAN HYPERSTIMULATION SYNDROME WITH LUNG COMPLICATION: CASE REPORT.

Norazilah MJ¹, Abdul Karim AK².

¹Obstetrics & Gynaecology Department, Faculty of Medicine, Universiti Teknologi MARA (UiTM), Sungai Buloh Campus, 47000 Jalan Hospital, Sungai Buloh, Selangor, Malaysia.

²Obstetrics and GynaecologyDepartment, Faculty of Medicine, Universiti Kebangsaan Malaysia, Cheras, Kuala Lumpur, Malaysia.

ABSTRACT

Ovarian hyperstimulation syndrome is an iatrogenic complication of ovarian stimulation cycle commonly used for in vitro fertilisation. Fluid shift due to capillary leakage causes a wide spectrum of presentation. The lung complication of ovarian hyperstimulation syndrome are reported in about 10 per cent of severe cases and isolated pleural effusion without ascites is rare. Herein we report two cases of severe ovarian hyperstimulation syndrome with pleural effusion. Both of them were normal responder of ovarian stimulation and presented with dyspnoea, nausea and vomiting. Clinical findings revealed reduced air entry of lung field and pleural effusion without significant ascites. Symptomatic management and thoracocentesis prevented further deterioration and helped in satisfactory recovery.

KEYWORDS: Complications, In vitro fertilisation (IVF), Ovarian hyperstimulation syndrome (OHSS), Pleural effusion.

Corresponding author: Norazilah binti Mat Jin, Obstetrics & Gynaecology Department, Faculty of Medicine, Universiti Teknologi MARA (UiTM), Sungai Buloh Campus, 47000 Jalan Hospital,

Sungai Buloh, Selangor, Malaysia.

Contact number: +603-6126 5000; Fax number: +603-6126 7073

Email: drnorazilah@uitm.edu.my

Brunei Int Med J. 2022;18:46-50