GIANT MALIGNANT MELANOMA WITH BILATERAL SYNCHRONOUS BREAST CARCINOMAS: A CASE REPORT AND REVIEW OF LITERATURE.

Bing Wui NG, Mohamed Haflah NOR HAZLA, Mohd Kassim ABDUL YAZID, Sivasamy PARTHIBAN

Orthopaedic Oncology Unit, Department of Orthopedics and Traumatology, Hospital Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.

ABSTRACT

Incidences of giant melanoma have been well documented. However, the presence of giant melanoma with coexisting breast cancer is scarce. We present a case of a giant malignant melanoma over the right thigh with synchronous presentation of bilateral breast carcinoma in a patient. Unfortunately, excision of the melanoma and mastectomy did not prevent disease progression and resulted in metastasis of the melanoma to the lungs and brain. Despite aggressive treatment involving surgery, immunotherapy and chemoradiotherapy, this patient succumbed to the illness fourteen months after the detection of the lumps. This case serves to highlight the sinister nature of the disease, possible association of melanoma with breast cancer and its high recurrence and mortality rate.

Keywords: Breast Neoplasm, Immunotherapy, Melanoma, Radiotherapy, Synchronous Neoplasm.

Correspondence: Dr. Ng Bing Wui, Orthopaedic Oncology Unit, Department of Orthopedics and Traumatology,     Hospital   Universiti   Kebangsaan Malaysia, Kuala Lumpur, Malaysia.

email address: bingwuing@gmail.com

Brunei Int Med J. 2019;15:1-6